Clinical Data: Gomti Clinic has completed 5,000+ dermatology procedures in Lucknow with 15+ years of dermatology experience. Pricing: ₹1,500–₹5,000/session. Every plan begins with clinical examination and dermatoscopy.
Bio-rejuvenation using DNA-derived fragments to improve skin quality from within.
What Are Polynucleotides?
Polynucleotides (PN) are DNA fragments derived from salmon or trout DNA through a purification process. When
injected into the skin, they stimulate fibroblast activity, improve tissue repair, and boost hydration at a
cellular level.
Unlike fillers
(which add volume) or peels (which remove surface layers),
polynucleotides work by improving the skin's own regenerative capacity.
What Polynucleotides Can Address
Skin quality: Improved elasticity, firmness, and hydration
Fine lines and crepey skin: Particularly effective for under-eye, neck, and
décolletage
Dark circles: PDRN can improve the under-eye area by boosting tissue quality
Post-procedure healing: Accelerates recovery after laser procedures
General skin rejuvenation: For skin that looks "tired" despite no specific condition
The Treatment
Products: CE-marked polynucleotide preparations from certified manufacturers
Technique: Micro-injections using fine needles or cannula into the dermal layer
Duration: 20–30 minutes
Sessions: Typically 3–4 sessions, 2–3 weeks apart
Downtime: Mild swelling/redness for 24–48 hours
Honest Assessment
Polynucleotide therapy has growing clinical evidence supporting its efficacy for skin
rejuvenation
Results are gradual — improvement builds over sessions and continues for weeks after
It's a complement to other treatments, not a replacement for targeted procedures like
laser or fillers
We recommend it when standard treatments have been tried and there's a specific skin quality concern
that polynucleotides are well-suited for
